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Time- and Dose-Dependent Effects of Ionizing Irradiation on the Membrane Expression of Hsp70 on Glioma Cells

The major stress-inducible protein Hsp70 (HSPA1A) is overexpressed in the cytosol of many highly aggressive tumor cells including glioblastoma multiforme and presented on their plasma membrane. Depending on its intracellular or membrane localization, Hsp70 either promotes tumor growth or serves as a...

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Detalles Bibliográficos
Autores principales: Fellinger, Helena, Stangl, Stefan, Hernandez Schnelzer, Alicia, Schwab, Melissa, Di Genio, Tommaso, Pieper, Marija, Werner, Caroline, Shevtsov, Maxim, Haller, Bernhard, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226755/
https://www.ncbi.nlm.nih.gov/pubmed/32276468
http://dx.doi.org/10.3390/cells9040912