Sex-Specific Regulation of miR-29b in the Myocardium Under Pressure Overload is Associated with Differential Molecular, Structural and Functional Remodeling Patterns in Mice and Patients with Aortic Stenosis

Pressure overload in patients with aortic stenosis (AS) induces an adverse remodeling of the left ventricle (LV) in a sex-specific manner. We assessed whether a sex-specific miR-29b dysregulation underlies this sex-biased remodeling pattern, as has been described in liver fibrosis. We studied mice w...

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Detalles Bibliográficos
Autores principales: García, Raquel, Salido-Medina, Ana B., Gil, Aritz, Merino, David, Gómez, Jenny, Villar, Ana V., González-Vílchez, Francisco, Hurlé, María A., Nistal, J. Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226763/
https://www.ncbi.nlm.nih.gov/pubmed/32235655
http://dx.doi.org/10.3390/cells9040833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226763/
https://www.ncbi.nlm.nih.gov/pubmed/32235655
http://dx.doi.org/10.3390/cells9040833

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