Impaired Metabolic Flexibility in the Osteoarthritis Process: A Study on Transmitochondrial Cybrids

Osteoarthritis (OA) is the most frequent joint disease; however, the etiopathogenesis is still unclear. Chondrocytes rely primarily on glycolysis to meet cellular energy demand, but studies implicate impaired mitochondrial function in OA pathogenesis. The relationship between mitochondrial dysfuncti...

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Detalles Bibliográficos
Autores principales: Dalmao-Fernández, Andrea, Lund, Jenny, Hermida-Gómez, Tamara, Vazquez-Mosquera, María E, Rego-Pérez, Ignacio, Blanco, Francisco J., Fernández-Moreno, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226768/
https://www.ncbi.nlm.nih.gov/pubmed/32230786
http://dx.doi.org/10.3390/cells9040809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226768/
https://www.ncbi.nlm.nih.gov/pubmed/32230786
http://dx.doi.org/10.3390/cells9040809

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