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Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer

BACKGROUND: Multidrug resistance (MDR) has been regarded as one of the major hurdles for the successful outcome of cancer chemotherapy. The collateral sensitivity (CS) effect is one the most auspicious anti-MDR strategies. Epoxylathyrane derivatives 1–16 were obtained by derivatization of the macroc...

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Detalles Bibliográficos
Autores principales: Reis, Mariana Alves, Matos, Ana M., Duarte, Noélia, Ahmed, Omar Bauomy, Ferreira, Ricardo J., Lage, Hermann, Ferreira, Maria-José U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226783/
https://www.ncbi.nlm.nih.gov/pubmed/32457612
http://dx.doi.org/10.3389/fphar.2020.00599