Nobiletin Promotes Megakaryocytic Differentiation through the MAPK/ERK-Dependent EGR1 Expression and Exerts Anti-Leukemic Effects in Human Chronic Myeloid Leukemia (CML) K562 Cells

Differentiation therapy is an alternative strategy used to induce the differentiation of blast cells toward mature cells and to inhibit tumor cell proliferation for cancer treatment. Nobiletin (NOB), a polymethoxyflavone phytochemical, is present abundantly in citrus peels and has been reported to p...

Descripción completa

Detalles Bibliográficos
Autores principales: Yen, Jui-Hung, Lin, Ching-Yen, Chuang, Chin-Hsien, Chin, Hsien-Kuo, Wu, Ming-Jiuan, Chen, Pei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226785/
https://www.ncbi.nlm.nih.gov/pubmed/32260160
http://dx.doi.org/10.3390/cells9040877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226785/
https://www.ncbi.nlm.nih.gov/pubmed/32260160
http://dx.doi.org/10.3390/cells9040877

Ejemplares similares