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Development of Mucosal PNAd(+) and MAdCAM-1(+) Venules during Disease Course in Ulcerative Colitis

PNAd and MAdCAM-1 addressins on venules are of importance in T-cell homing and potential therapeutic targets in ulcerative colitis (UC). Normally, PNAd(+) high endothelial venules (HEVs) are only present in lymphoid organs, whereas small numbers of MAdCAM-1(+) venules can be seen in non-lymphoid tis...

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Detalles Bibliográficos
Autores principales: Roosenboom, Britt, van Lochem, Ellen G., Meijer, Jos, Smids, Carolijn, Nierkens, Stefan, Brand, Eelco C., van Erp, Liselot W., Kemperman, Larissa G.J.M., Groenen, Marcel J.M., Horjus Talabur Horje, Carmen S., Wahab, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226824/
https://www.ncbi.nlm.nih.gov/pubmed/32268498
http://dx.doi.org/10.3390/cells9040891