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Modulation of STAT3 Signaling, Cell Redox Defenses and Cell Cycle Checkpoints by β-Caryophyllene in Cholangiocarcinoma Cells: Possible Mechanisms Accounting for Doxorubicin Chemosensitization and Chemoprevention

Cholangiocarcinoma (CCA) is an aggressive group of biliary tract cancers, characterized by late diagnosis, low effective chemotherapies, multidrug resistance, and poor outcomes. In the attempt to identify new therapeutic strategies for CCA, we studied the antiproliferative activity of a combination...

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Detalles Bibliográficos
Autores principales: Di Sotto, Antonella, Di Giacomo, Silvia, Rubini, Elisabetta, Macone, Alberto, Gulli, Marco, Mammola, Caterina Loredana, Eufemi, Margherita, Mancinelli, Romina, Mazzanti, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226839/
https://www.ncbi.nlm.nih.gov/pubmed/32252311
http://dx.doi.org/10.3390/cells9040858