Noggin Inhibits IL-1β and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis

Osteoarthritis (OA) is a chronic inflammatory and progressive joint disease that results in cartilage degradation and subchondral bone remodeling. The proinflammatory cytokine interleukin 1 beta (IL-1β) is abundantly expressed in OA and plays a crucial role in cartilage remodeling, although its role...

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Detalles Bibliográficos
Autores principales: Chien, Szu-Yu, Tsai, Chun-Hao, Liu, Shan-Chi, Huang, Chien-Chung, Lin, Tzu-Hung, Yang, Yu-Zhen, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226847/
https://www.ncbi.nlm.nih.gov/pubmed/32290085
http://dx.doi.org/10.3390/cells9040927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226847/
https://www.ncbi.nlm.nih.gov/pubmed/32290085
http://dx.doi.org/10.3390/cells9040927

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