Deletion of P2X7 Receptor Decreases Basal Glutathione Level by Changing Glutamate-Glutamine Cycle and Neutral Amino Acid Transporters

Glutathione (GSH) is an endogenous tripeptide antioxidant that consists of glutamate-cysteine-glycine. GSH content is limited by the availability of glutamate and cysteine. Furthermore, glutamine is involved in the regulation of GSH synthesis via the glutamate–glutamine cycle. P2X7 receptor (P2X7R)...

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Detalles Bibliográficos
Autores principales: Park, Hana, Kim, Ji-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226967/
https://www.ncbi.nlm.nih.gov/pubmed/32316268
http://dx.doi.org/10.3390/cells9040995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226967/
https://www.ncbi.nlm.nih.gov/pubmed/32316268
http://dx.doi.org/10.3390/cells9040995

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