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CRISPR/Cas9 Epigenome Editing Potential for Rare Imprinting Diseases: A Review

Imprinting diseases (IDs) are rare congenital disorders caused by aberrant dosages of imprinted genes. Rare IDs are comprised by a group of several distinct disorders that share a great deal of homology in terms of genetic etiologies and symptoms. Disruption of genetic or epigenetic mechanisms can c...

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Detalles Bibliográficos
Autores principales: Syding, Linn Amanda, Nickl, Petr, Kasparek, Petr, Sedlacek, Radislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226972/
https://www.ncbi.nlm.nih.gov/pubmed/32316223
http://dx.doi.org/10.3390/cells9040993