Differences in the Response to DNA Double-Strand Breaks between Rod Photoreceptors of Rodents, Pigs, and Humans

Genome editing (GE) represents a powerful approach to fight inherited blinding diseases in which the underlying mutations cause the degeneration of the light sensing photoreceptor cells of the retina. Successful GE requires the efficient repair of DNA double-stranded breaks (DSBs) generated during t...

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Detalles Bibliográficos
Autores principales: Frohns, Florian, Frohns, Antonia, Kramer, Johanna, Meurer, Katharina, Rohrer-Bley, Carla, Solovei, Irina, Hicks, David, Layer, Paul G., Löbrich, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226979/
https://www.ncbi.nlm.nih.gov/pubmed/32290532
http://dx.doi.org/10.3390/cells9040947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226979/
https://www.ncbi.nlm.nih.gov/pubmed/32290532
http://dx.doi.org/10.3390/cells9040947

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