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The Catalytic-Dependent and -Independent Roles of Lsd1 and Lsd2 Lysine Demethylases in Heterochromatin Formation in Schizosaccharomyces pombe

In eukaryotes, heterochromatin plays a critical role in organismal development and cell fate acquisition, through regulating gene expression. The evolutionarily conserved lysine-specific demethylases, Lsd1 and Lsd2, remove mono- and dimethylation on histone H3, serving complex roles in gene expressi...

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Detalles Bibliográficos
Autores principales: Marayati, Bahjat F., Tucker, James F., De La Cerda, David A., Hou, Tien-Chi, Chen, Rong, Sugiyama, Tomoyasu, Pease, James B., Zhang, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226997/
https://www.ncbi.nlm.nih.gov/pubmed/32295063
http://dx.doi.org/10.3390/cells9040955