Congenital Tufting Enteropathy-Associated Mutant of Epithelial Cell Adhesion Molecule Activates the Unfolded Protein Response in a Murine Model of the Disease

Congenital tufting enteropathy (CTE) is a rare chronic diarrheal disease of infancy caused by mutations in epithelial cell adhesion molecule (EpCAM). Previously, a murine CTE model showed mis-localization of EpCAM away from the basolateral cell surface in the intestine. Here we demonstrate that muta...

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Detalles Bibliográficos
Autores principales: Das, Barun, Okamoto, Kevin, Rabalais, John, Marchelletta, Ronald R., Barrett, Kim E., Das, Soumita, Niwa, Maho, Sivagnanam, Mamata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226999/
https://www.ncbi.nlm.nih.gov/pubmed/32290509
http://dx.doi.org/10.3390/cells9040946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226999/
https://www.ncbi.nlm.nih.gov/pubmed/32290509
http://dx.doi.org/10.3390/cells9040946

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