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Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy

Cathepsins (CTSs) are ubiquitously expressed proteases normally found in the endolysosomal compartment where they mediate protein degradation and turnover. However, CTSs are also found in the cytoplasm, nucleus, and extracellular matrix where they actively participate in cell signaling, protein proc...

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Detalles Bibliográficos
Autores principales: De Pasquale, Valeria, Moles, Anna, Pavone, Luigi Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227001/
https://www.ncbi.nlm.nih.gov/pubmed/32326609
http://dx.doi.org/10.3390/cells9040979