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BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux

Impaired autophagy has been shown to play a critical role in experimental and human acute pancreatitis (AP). However, the mechanism for transcriptional regulation of autophagy remains largely unknown. In this study, we aim to explore the role of BRD4 (bromodomain-containing protein 4), a transcripti...

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Detalles Bibliográficos
Autores principales: Shen, Shuangjun, Li, Bin, Dai, Juanjuan, Wu, Zengkai, He, Yan, Wen, Li, Wang, Xingpeng, Hu, Guoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227015/
https://www.ncbi.nlm.nih.gov/pubmed/32457617
http://dx.doi.org/10.3389/fphar.2020.00618