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The effect of nicotinamide adenine dinucleotide phosphate oxidase 4 on migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

BACKGROUND: Reactive oxygen species (ROS) regulate the migration and invasion of fibroblast-like synoviocytes (FLS), which are key effector cells in rheumatoid arthritis (RA) pathogenesis. Nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) induces ROS generation and, consequently, enhances...

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Detalles Bibliográficos
Autores principales: Lee, Ha-Reum, Yoo, Su-Jin, Kim, Jinhyun, Yoo, In Seol, Park, Chan Keol, Kang, Seong Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227051/
https://www.ncbi.nlm.nih.gov/pubmed/32414400
http://dx.doi.org/10.1186/s13075-020-02204-0