Upregulation of pERK and c-JUN by γ-tocotrienol and not α-tocopherol are essential to the differential effect on apoptosis in prostate cancer cells

BACKGROUND: α-tocopherol (AT) and γ-tocotrienol (GT3) are vitamin E isoforms considered to have potential chemopreventive properties. AT has been widely studied in vitro and in clinical trials with mixed results. The latest clinical study (SELECT trial) tested AT in prostate cancer patients, determi...

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Detalles Bibliográficos
Autores principales: Moore, Christine, Palau, Victoria E., Mahboob, Rashid, Lightner, Janet, Stone, William, Krishnan, Koyamangalath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227069/
https://www.ncbi.nlm.nih.gov/pubmed/32414345
http://dx.doi.org/10.1186/s12885-020-06947-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227069/
https://www.ncbi.nlm.nih.gov/pubmed/32414345
http://dx.doi.org/10.1186/s12885-020-06947-6

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