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PPFIA1 expression associates with poor response to endocrine treatment in luminal breast cancer

BACKGROUND: PPFIA1 is an important regulator of cell migration and invasion, regulating focal adhesion signalling and disassembly. PPFIA1 is frequently amplified in breast cancer, and recent functional studies indicate that PPFIA1 is an important promoter of migration and invasion in breast cancer....

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Detalles Bibliográficos
Autores principales: Alfarsi, Lutfi H., El Ansari, Rokaya, Craze, Madeleine L., Masisi, Brendah K., Ellis, Ian O., Rakha, Emad A., Green, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227113/
https://www.ncbi.nlm.nih.gov/pubmed/32410585
http://dx.doi.org/10.1186/s12885-020-06939-6