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Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

BACKGROUND/AIMS: Dose-escalation studies are essential in the early stages of developing novel treatments, when the aim is to find a safe dose for administration in humans. Despite their great importance, many dose-escalation studies use study designs based on heuristic algorithms with well-document...

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Detalles Bibliográficos
Autores principales: Pallmann, Philip, Wan, Fang, Mander, Adrian P, Wheeler, Graham M, Yap, Christina, Clive, Sally, Hampson, Lisa V, Jaki, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227124/
https://www.ncbi.nlm.nih.gov/pubmed/31856600
http://dx.doi.org/10.1177/1740774519890146