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Graphene oxide suppresses the growth and malignancy of glioblastoma stem cell-like spheroids via epigenetic mechanisms

BACKGROUND: Glioblastoma stem-like cells (GSCs) are hypothesized to contribute to self-renewal and therapeutic resistance in glioblastoma multiforme (GBM) tumors. Constituting only a small percentage of cancer cells, GSCs possess “stem-like”, tumor-initiating properties and display resistance to irr...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Zhou, Wenjuan, Li, Xian, Ren, Jun, Ji, Guangyu, Du, Jingyi, Tian, Wenyu, Liu, Qian, Hao, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227195/
https://www.ncbi.nlm.nih.gov/pubmed/32410622
http://dx.doi.org/10.1186/s12967-020-02359-z