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Restoration of miR-193a expression is tumor-suppressive in MYC amplified Group 3 medulloblastoma
Medulloblastoma, a highly malignant pediatric brain tumor, consists of four molecular subgroups, namely WNT, SHH, Group 3, and Group 4. The expression of miR-193a, a WNT subgroup-specific microRNA, was found to be induced by MYC, an oncogenic target of the canonical WNT signaling. MiR-193a is not ex...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227220/ https://www.ncbi.nlm.nih.gov/pubmed/32410663 http://dx.doi.org/10.1186/s40478-020-00942-5 |