Restoration of miR-193a expression is tumor-suppressive in MYC amplified Group 3 medulloblastoma

Medulloblastoma, a highly malignant pediatric brain tumor, consists of four molecular subgroups, namely WNT, SHH, Group 3, and Group 4. The expression of miR-193a, a WNT subgroup-specific microRNA, was found to be induced by MYC, an oncogenic target of the canonical WNT signaling. MiR-193a is not ex...

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Detalles Bibliográficos
Autores principales: Bharambe, Harish Shrikrishna, Joshi, Annada, Yogi, Kedar, Kazi, Sadaf, Shirsat, Neelam Vishwanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227220/
https://www.ncbi.nlm.nih.gov/pubmed/32410663
http://dx.doi.org/10.1186/s40478-020-00942-5

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