Hybrid Stem Cell States: Insights Into the Relationship Between Mammary Development and Breast Cancer Using Single-Cell Transcriptomics

Similarities between stem cells and cancer cells have implicated mammary stem cells in breast carcinogenesis. Recent evidence suggests that normal breast stem cells exist in multiple phenotypic states: epithelial, mesenchymal, and hybrid epithelial/mesenchymal (E/M). Hybrid E/M cells in particular h...

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Detalles Bibliográficos
Autores principales: Thong, Tasha, Wang, Yutong, Brooks, Michael D., Lee, Christopher T., Scott, Clayton, Balzano, Laura, Wicha, Max S., Colacino, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227401/
https://www.ncbi.nlm.nih.gov/pubmed/32457901
http://dx.doi.org/10.3389/fcell.2020.00288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227401/
https://www.ncbi.nlm.nih.gov/pubmed/32457901
http://dx.doi.org/10.3389/fcell.2020.00288

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