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Measuring Intratumoral Heterogeneity of Immune Repertoires

There is considerable clinical and fundamental value in measuring the clonal heterogeneity of T and B cell expansions in tumors and tumor-associated lymphoid structures—along with the associated heterogeneity of the tumor neoantigen landscape—but such analyses remain challenging to perform. Here, we...

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Detalles Bibliográficos
Autores principales: Yuzhakova, Diana Vladimirovna, Volchkova, Lilia N., Pogorelyy, Mikhail Valerievich, Serebrovskaya, Ekaterina O., Shagina, Irina A., Bryushkova, Ekaterina A., Nakonechnaya, Tatiana O., Izosimova, Anna V., Zavyalova, Daria S., Karabut, Maria M., Izraelson, Mark, Samoylenko, Igor V., Zagainov, Vladimir E., Chudakov, Dmitriy M., Zagaynova, Elena V., Sharonov, George Vladimirovich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227437/
https://www.ncbi.nlm.nih.gov/pubmed/32457825
http://dx.doi.org/10.3389/fonc.2020.00512