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A dendritic cell-targeted chimeric hepatitis B virus immunotherapeutic vaccine induces both cellular and humoral immune responses in vivo

Chimigen® HBV Immunotherapeutic Vaccine (C-HBV), a recombinant chimeric fusion protein comprising hepatitis B virus (HBV) S1 and S2 surface antigen fragments, Core antigen and a murine monoclonal antibody heavy chain fragment (Fc), was designed and produced in Sf9 insect cells. C-HBV targets the hos...

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Detalles Bibliográficos
Autores principales: George, Rajan, Ma, Allan, Motyka, Bruce, Shi, Yuenian Eric, Liu, Qiang, Griebel, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227651/
https://www.ncbi.nlm.nih.gov/pubmed/31687875
http://dx.doi.org/10.1080/21645515.2019.1689081