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Characterisation of alternative expression vectors for recombinant Bacillus Calmette-Guérin as live bacterial delivery systems

BACKGROUND: Bacillus Calmette-Guérin (BCG) is considered a promising live bacterial delivery system. However, several proposals for rBCG vaccines have not progressed, mainly due to the limitations of the available expression systems. OBJECTIVES: To obtain a set of mycobacterial vectors using a range...

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Detalles Bibliográficos
Autores principales: Nascimento, Larissa V, Santos, Carina C, Leite, Luciana CC, Nascimento, Ivan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227789/
https://www.ncbi.nlm.nih.gov/pubmed/32428188
http://dx.doi.org/10.1590/0074-02760190347