Cascade CuH-Catalysed Conversion of Alkynes to Enantioenriched 1,1-Disubstituted Products

Enantioenriched α-aminoboronic acids play a unique role in medicinal chemistry and have emerged as privileged pharmacophores in proteasome inhibitors. Additionally, they represent synthetically useful chiral building blocks in organic synthesis. Recently, CuH-catalyzed asymmetric alkene hydrofunctio...

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Detalles Bibliográficos
Autores principales: Gao, De-Wei, Gao, Yang, Shao, Huiling, Qiao, Tian-Zhang, Wang, Xin, Sanchez, Brittany B., Chen, Jason S., Liu, Peng, Engle, Keary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227802/
https://www.ncbi.nlm.nih.gov/pubmed/32420528
http://dx.doi.org/10.1038/s41929-019-0384-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227802/
https://www.ncbi.nlm.nih.gov/pubmed/32420528
http://dx.doi.org/10.1038/s41929-019-0384-6

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