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Cascade CuH-Catalysed Conversion of Alkynes to Enantioenriched 1,1-Disubstituted Products
Enantioenriched α-aminoboronic acids play a unique role in medicinal chemistry and have emerged as privileged pharmacophores in proteasome inhibitors. Additionally, they represent synthetically useful chiral building blocks in organic synthesis. Recently, CuH-catalyzed asymmetric alkene hydrofunctio...
Autores principales: | Gao, De-Wei, Gao, Yang, Shao, Huiling, Qiao, Tian-Zhang, Wang, Xin, Sanchez, Brittany B., Chen, Jason S., Liu, Peng, Engle, Keary M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227802/ https://www.ncbi.nlm.nih.gov/pubmed/32420528 http://dx.doi.org/10.1038/s41929-019-0384-6 |
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