Design of composite measure schemes for comparative severity assessment in animal-based neuroscience research: A case study focussed on rat epilepsy models

Comparative severity assessment of animal models and experimental interventions is of utmost relevance for harm-benefit analysis during ethical evaluation, an animal welfare-based model prioritization as well as the validation of refinement measures. Unfortunately, there is a lack of evidence-based...

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Detalles Bibliográficos
Autores principales: van Dijk, Roelof Maarten, Koska, Ines, Bleich, Andre, Tolba, Rene, Seiffert, Isabel, Möller, Christina, Di Liberto, Valentina, Talbot, Steven Roger, Potschka, Heidrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228039/
https://www.ncbi.nlm.nih.gov/pubmed/32413036
http://dx.doi.org/10.1371/journal.pone.0230141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228039/
https://www.ncbi.nlm.nih.gov/pubmed/32413036
http://dx.doi.org/10.1371/journal.pone.0230141

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