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How global DNA unwinding causes non-uniform stress distribution and melting of DNA
DNA unwinding is an important process that controls binding of proteins, gene expression and melting of double-stranded DNA. In a series of all-atom MD simulations on two DNA molecules containing a transcription start TATA-box sequence we demonstrate that application of a global restraint on the DNA...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228070/ https://www.ncbi.nlm.nih.gov/pubmed/32413048 http://dx.doi.org/10.1371/journal.pone.0232976 |