High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda

INTRODUCTION: Susceptibility testing for pyrazinamide (PZA), a cornerstone anti-TB drug is not commonly done in Uganda because it is expensive and characterized with technical difficulties thus resistance to this drug is less studied. Resistance is commonly associated with mutations in the pncA gene...

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Detalles Bibliográficos
Autores principales: Naluyange, Resty, Mboowa, Gerald, Komakech, Kevin, Semugenze, Derrick, Kateete, David Patrick, Ssengooba, Willy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228079/
https://www.ncbi.nlm.nih.gov/pubmed/32413052
http://dx.doi.org/10.1371/journal.pone.0232543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228079/
https://www.ncbi.nlm.nih.gov/pubmed/32413052
http://dx.doi.org/10.1371/journal.pone.0232543

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