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High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda
INTRODUCTION: Susceptibility testing for pyrazinamide (PZA), a cornerstone anti-TB drug is not commonly done in Uganda because it is expensive and characterized with technical difficulties thus resistance to this drug is less studied. Resistance is commonly associated with mutations in the pncA gene...
Autores principales: | Naluyange, Resty, Mboowa, Gerald, Komakech, Kevin, Semugenze, Derrick, Kateete, David Patrick, Ssengooba, Willy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228079/ https://www.ncbi.nlm.nih.gov/pubmed/32413052 http://dx.doi.org/10.1371/journal.pone.0232543 |
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