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The transition from local to global patterns governs the differentiation of mouse blastocysts

During mammalian blastocyst development, inner cell mass (ICM) cells differentiate into epiblast (Epi) or primitive endoderm (PrE). These two fates are characterized by the expression of the transcription factors NANOG and GATA6, respectively. Here, we investigate the spatio-temporal distribution of...

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Detalles Bibliográficos
Autores principales: Fischer, Sabine C., Corujo-Simon, Elena, Lilao-Garzon, Joaquin, Stelzer, Ernst H. K., Muñoz-Descalzo, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228118/
https://www.ncbi.nlm.nih.gov/pubmed/32413083
http://dx.doi.org/10.1371/journal.pone.0233030