Evaluating the Role of the Steroid and Xenobiotic Receptor (SXR/PXR) in PCB-153 Metabolism and Protection against Associated Adverse Effects during Perinatal and Chronic Exposure in Mice

BACKGROUND: Polychlorinated biphenyls (PCBs) are environmental toxicants; PCB exposure has been associated with adverse effects on wildlife and humans. However, the mechanisms underlying these adverse effects are not fully understood. The steroid and xenobiotic receptor [SXR; also known as the pregn...

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Detalles Bibliográficos
Autores principales: Egusquiza, Riann Jenay, Ambrosio, Maria Elena, Wang, Shuyi Gin, Kay, Kaelen Marie, Zhang, Chunyun, Lehmler, Hans-Joachim, Blumberg, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228131/
https://www.ncbi.nlm.nih.gov/pubmed/32352317
http://dx.doi.org/10.1289/EHP6262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228131/
https://www.ncbi.nlm.nih.gov/pubmed/32352317
http://dx.doi.org/10.1289/EHP6262

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