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Human papillomavirus E7 binds Oct4 and regulates its activity in HPV-associated cervical cancers

Octamer binding transcription factor-4 (Oct4), is highly expressed in stem cells and has indispensable roles in pluripotency and cellular reprogramming. In contrast to other factors used for cellular reprogramming, a role for Oct4 outside embryonic stem cells has been elusive and highly controversia...

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Detalles Bibliográficos
Autores principales: Panayiotou, Theofano, Michael, Stella, Zaravinos, Apostolos, Demirag, Ece, Achilleos, Charis, Strati, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228134/
https://www.ncbi.nlm.nih.gov/pubmed/32298395
http://dx.doi.org/10.1371/journal.ppat.1008468