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Impact of a preceding radiotherapy on the outcome of immune checkpoint inhibition in metastatic melanoma: a multicenter retrospective cohort study of the DeCOG

BACKGROUND: Immune checkpoint inhibition (ICI) is an essential treatment option in melanoma. Its outcome may be improved by a preceding radiation of metastases. This study aimed to investigate the impact of a preceding radiotherapy on the clinical outcome of ICI treatment. METHODS: This multicenter...

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Detalles Bibliográficos
Autores principales: Knispel, Sarah, Stang, Andreas, Zimmer, Lisa, Lax, Hildegard, Gutzmer, Ralf, Heinzerling, Lucie, Weishaupt, Carsten, Pföhler, Claudia, Gesierich, Anja, Herbst, Rudolf, Kaehler, Katharina C, Weide, Benjamin, Berking, Carola, Loquai, Carmen, Utikal, Jochen, Terheyden, Patrick, Kaatz, Martin, Schlaak, Max, Kreuter, Alexander, Ulrich, Jens, Mohr, Peter, Dippel, Edgar, Livingstone, Elisabeth, Becker, Jürgen C, Weichenthal, Michael, Chorti, Eleftheria, Gronewold, Janine, Schadendorf, Dirk, Ugurel, Selma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228559/
https://www.ncbi.nlm.nih.gov/pubmed/32371460
http://dx.doi.org/10.1136/jitc-2019-000395