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PDCD4 deficiency ameliorates left ventricular remodeling and insulin resistance in a rat model of type 2 diabetic cardiomyopathy

OBJECTIVE: Diabetic cardiomyopathy (DCM) is characterized by cardiac remodeling, dysfunction, and insulin resistance; however, the underlying mechanism has not been fully elucidated. Programmed cell death 4 (PDCD4) is a novel inflammation and apoptosis gene, but its role in type 2 DCM remains elusiv...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Zhang, Meng, Yang, Zhi, Huang, Shanying, Wu, Xiao, Cao, Lei, Wang, Xiaohong, Li, Qian, Li, Na, Gao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228667/
https://www.ncbi.nlm.nih.gov/pubmed/32371529
http://dx.doi.org/10.1136/bmjdrc-2019-001081