The activity of sulfono-γ-AApeptide helical foldamers that mimic GLP-1

Existing long α-helix mimicking necessitates the retention of most natural amino acid residues to maintain their biological activity. Here, we report the exploration of helical sulfono-γ-AApeptides with entire unnatural backbones for their ability to structurally and functionally mimic glucagon-like...

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Detalles Bibliográficos
Autores principales: Sang, Peng, Zhou, Zhihong, Shi, Yan, Lee, Candy, Amso, Zaid, Huang, David, Odom, Timothy, Nguyen-Tran, Vân T.B., Shen, Weijun, Cai, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228743/
https://www.ncbi.nlm.nih.gov/pubmed/32440547
http://dx.doi.org/10.1126/sciadv.aaz4988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228743/
https://www.ncbi.nlm.nih.gov/pubmed/32440547
http://dx.doi.org/10.1126/sciadv.aaz4988

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