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Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti–PD-L1 immunotherapy
Anti–programmed cell death 1 ligand 1 (PD-L1) therapy is extraordinarily effective in select patients with cancer. However, insufficient lymphocytic infiltration, weak T cell–induced inflammation, and immunosuppressive cell accumulation in the tumor microenvironment (TME) may greatly diminish the ef...
Autores principales: | Li, Zhaoting, Wang, Yixin, Shen, Yuexin, Qian, Chenggen, Oupicky, David, Sun, Minjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228744/ https://www.ncbi.nlm.nih.gov/pubmed/32440550 http://dx.doi.org/10.1126/sciadv.aaz9240 |
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