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Legionella effector AnkX displaces the switch II region for Rab1b phosphocholination

The causative agent of Legionnaires disease, Legionella pneumophila, translocates the phosphocholine transferase AnkX during infection and thereby posttranslationally modifies the small guanosine triphosphatase (GTPase) Rab1 with a phosphocholine moiety at S76 using cytidine diphosphate (CDP)–cholin...

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Detalles Bibliográficos
Autores principales: Ernst, Stefan, Ecker, Felix, Kaspers, Marietta S., Ochtrop, Philipp, Hedberg, Christian, Groll, Michael, Itzen, Aymelt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228754/
https://www.ncbi.nlm.nih.gov/pubmed/32440549
http://dx.doi.org/10.1126/sciadv.aaz8041