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A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking

CD81 and its binding partner CD19 are core subunits of the B cell co-receptor complex. While CD19 belongs to the extensively studied Ig superfamily, CD81 belongs to a poorly understood family of four-pass transmembrane proteins called tetraspanins. Tetraspanins play important physiological roles by...

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Detalles Bibliográficos
Autores principales: Susa, Katherine J, Seegar, Tom CM, Blacklow, Stephen C, Kruse, Andrew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228769/
https://www.ncbi.nlm.nih.gov/pubmed/32338599
http://dx.doi.org/10.7554/eLife.52337