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Performance of an acoustic settler versus a hollow fiber–based ATF technology for influenza virus production in perfusion

ABSTRACT: Process intensification and integration is crucial regarding an ever increasing pressure on manufacturing costs and capacities in biologics manufacturing. For virus production in perfusion mode, membrane-based alternating tangential flow filtration (ATF) and acoustic settler are the common...

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Detalles Bibliográficos
Autores principales: Gränicher, Gwendal, Coronel, Juliana, Trampler, Felix, Jordan, Ingo, Genzel, Yvonne, Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228903/
https://www.ncbi.nlm.nih.gov/pubmed/32291490
http://dx.doi.org/10.1007/s00253-020-10596-x