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Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes

Proteasomes are the main producers of antigenic peptides presented to CD8(+) T cells. They can cut proteins and release their fragments or recombine non-contiguous fragments thereby generating novel sequences, i.e. spliced peptides. Understanding which are the driving forces and the sequence prefere...

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Detalles Bibliográficos
Autores principales: Specht, Gerd, Roetschke, Hanna P., Mansurkhodzhaev, Artem, Henklein, Petra, Textoris-Taube, Kathrin, Urlaub, Henning, Mishto, Michele, Liepe, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228940/
https://www.ncbi.nlm.nih.gov/pubmed/32415162
http://dx.doi.org/10.1038/s41597-020-0487-6