SMAD4 activates Wnt signaling pathway to inhibit granulosa cell apoptosis

The TGF-β and Wnt signaling pathways are interrelated in many cell types and tissues, and control cell functions in coordination. Here, we report that SMAD4, a downstream effector of the TGF-β signaling pathway, induces FZD4, a receptor of the Wnt signaling pathway, establishing a novel route of com...

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Detalles Bibliográficos
Autores principales: Du, Xing, Li, Qiqi, Yang, Liu, Liu, Lu, Cao, Qiuyu, Li, Qifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228950/
https://www.ncbi.nlm.nih.gov/pubmed/32415058
http://dx.doi.org/10.1038/s41419-020-2578-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228950/
https://www.ncbi.nlm.nih.gov/pubmed/32415058
http://dx.doi.org/10.1038/s41419-020-2578-x

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