ERCC1–XPF targeting to psoralen–DNA crosslinks depends on XPA and FANCD2

The effectiveness of many DNA-damaging chemotherapeutic drugs depends on their ability to form monoadducts, intrastrand crosslinks and/or interstrand crosslinks (ICLs) that interfere with transcription and replication. The ERCC1–XPF endonuclease plays a critical role in removal of these lesions by i...

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Detalles Bibliográficos
Autores principales: Sabatella, Mariangela, Pines, Alex, Slyskova, Jana, Vermeulen, Wim, Lans, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228994/
https://www.ncbi.nlm.nih.gov/pubmed/31392348
http://dx.doi.org/10.1007/s00018-019-03264-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228994/
https://www.ncbi.nlm.nih.gov/pubmed/31392348
http://dx.doi.org/10.1007/s00018-019-03264-5

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