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ERCC1–XPF targeting to psoralen–DNA crosslinks depends on XPA and FANCD2
The effectiveness of many DNA-damaging chemotherapeutic drugs depends on their ability to form monoadducts, intrastrand crosslinks and/or interstrand crosslinks (ICLs) that interfere with transcription and replication. The ERCC1–XPF endonuclease plays a critical role in removal of these lesions by i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228994/ https://www.ncbi.nlm.nih.gov/pubmed/31392348 http://dx.doi.org/10.1007/s00018-019-03264-5 |