Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8(+) T cells and exhibit a distinct CD95(hi) B cell phenotype

AIMS/HYPOTHESIS: The aim of this study was to characterise islet autoantibody profiles and immune cell phenotypes in slow progressors to type 1 diabetes. METHODS: Immunological variables were compared across peripheral blood samples obtained from slow progressors to type 1 diabetes, individuals with...

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Detalles Bibliográficos
Autores principales: Hanna, Stephanie J., Powell, Wendy E., Long, Anna E., Robinson, Emma J. S., Davies, Joanne, Megson, Clare, Howell, Alexandra, Jones, Taz J., Ladell, Kristin, Price, David A., Dayan, Colin M., Williams, Alistair J. K., Gillespie, Kathleen M., Wong, F. Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228996/
https://www.ncbi.nlm.nih.gov/pubmed/32157332
http://dx.doi.org/10.1007/s00125-020-05114-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228996/
https://www.ncbi.nlm.nih.gov/pubmed/32157332
http://dx.doi.org/10.1007/s00125-020-05114-7

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