Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and virulence. Here, we show that Agd3 deacetylates GAG...

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Detalles Bibliográficos
Autores principales: Bamford, Natalie C., Le Mauff, François, Van Loon, Jaime C., Ostapska, Hanna, Snarr, Brendan D., Zhang, Yongzhen, Kitova, Elena N., Klassen, John S., Codée, Jeroen D. C., Sheppard, Donald C., Howell, P. Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229062/
https://www.ncbi.nlm.nih.gov/pubmed/32415073
http://dx.doi.org/10.1038/s41467-020-16144-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229062/
https://www.ncbi.nlm.nih.gov/pubmed/32415073
http://dx.doi.org/10.1038/s41467-020-16144-5

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