A role for actin flexibility in thin filament-mediated contractile regulation and myopathy

Striated muscle contraction is regulated by the translocation of troponin-tropomyosin strands over the thin filament surface. Relaxation relies partly on highly-favorable, conformation-dependent electrostatic contacts between actin and tropomyosin, which position tropomyosin such that it impedes act...

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Detalles Bibliográficos
Autores principales: Viswanathan, Meera C., Schmidt, William, Franz, Peter, Rynkiewicz, Michael J., Newhard, Christopher S., Madan, Aditi, Lehman, William, Swank, Douglas M., Preller, Matthias, Cammarato, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229152/
https://www.ncbi.nlm.nih.gov/pubmed/32415060
http://dx.doi.org/10.1038/s41467-020-15922-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229152/
https://www.ncbi.nlm.nih.gov/pubmed/32415060
http://dx.doi.org/10.1038/s41467-020-15922-5

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