The route to transcription initiation determines the mode of transcriptional bursting in E. coli

Transcription is fundamentally noisy, leading to significant heterogeneity across bacterial populations. Noise is often attributed to burstiness, but the underlying mechanisms and their dependence on the mode of promotor regulation remain unclear. Here, we measure E. coli single cell mRNA levels for...

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Detalles Bibliográficos
Autores principales: Engl, Christoph, Jovanovic, Goran, Brackston, Rowan D., Kotta-Loizou, Ioly, Buck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229158/
https://www.ncbi.nlm.nih.gov/pubmed/32415118
http://dx.doi.org/10.1038/s41467-020-16367-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229158/
https://www.ncbi.nlm.nih.gov/pubmed/32415118
http://dx.doi.org/10.1038/s41467-020-16367-6

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